Aliases &
Descriptions
for IAH1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)1 2 | | isoamyl acetate-hydrolyzing esterase 1 homolog2 | | MGC1028602 | | EC 3.1.-.-3 | | S5 |
Export aliases for IAH1 gene to outside databases |
Summaries
for IAH1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: IAH1_HUMAN, Q2TAA2Function: Probable lipase (By similarity)
|
Genomic Views
for IAH1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for IAH1
Other transcription factors
Search SABiosciences Chromatin IP Primers for IAH1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for IAH1  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2p25.1 Ensembl cytogenetic band: 2p25.1 HGNC cytogenetic band: 2p25.1IAH1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02P009533: view genomic region
(about GC identifiers)
Start:
|
9,460,193 bp from pter |
End:
|
9,474,097 bp from pter |
Size:
|
13,905 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr2+ 9,613,787-9,636,672 |
RefSeq DNA sequence:- NC_000002.11 NT_005334.16
|
Proteins
for IAH1 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: IAH1_HUMAN, Q2TAA2 (See
protein sequence)Recommended Name: Isoamyl acetate-hydrolyzing esterase 1 homolog Size: 248 amino acids; 27599 DaExplore the universe of human proteins at neXtProt for IAH1: NX_Q2TAA2
REFSEQ proteins: NP_001034702.1
ENSEMBL proteins: ENSP00000419224 ENSP00000420532 ENSP00000418492 ENSP00000314400 ENSP00000417580 ENSP00000419807 ENSP00000420562 ENSP00000419110 ENSP00000419368 ENSP00000382060
Human Recombinant Proteins
Antibodies for IAH1:
Assays for IAH1: |
Protein
Domains/
Families
for IAH1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
IAH1 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q2TAA2ProtoNet protein and cluster: Q2TAA2 1 Blocks protein family: IPB001087 Lipolytic enzyme
UniProtKB/Swiss-Prot: IAH1_HUMAN, Q2TAA2Similarity: Belongs to the 'GDSL' lipolytic enzyme family. IAH1 subfamily |
Gene Function
for IAH1 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
UniProtKB/Swiss-Prot: IAH1_HUMAN, Q2TAA2Function: Probable lipase (By similarity)Enzyme Number (IUBMB): EC 3.1.-.-
1 Gene Ontology (GO) molecular function term (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016788 | hydrolase activity, acting on ester bonds |
IEA | -- |
About this table
IAH1 for ontologies About GeneDecksing
|
Pathways & Interactions
for IAH1 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
SABiosciences Custom Pathway-Focused PCR Arrays for IAH1
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IAH1
2 Gene Ontology (GO) biological process terms (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006629 | lipid metabolic process |
-- | -- | | GO:0016042 | lipid catabolic process |
IEA | -- |
About this table
IAH1 for ontologies About GeneDecksing
|
Drugs & Compounds
for IAH1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for IAH1
|
Transcripts
for IAH1 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for IAH1 gene: NM_001039613.1 Additional cDNA sequence: AK074513.1 AK092982.1 AK291984.1 AK297648.1 BC019061.1 BC039709.1 BC059410.1 BC067865.1 BC111025.1 CR621865.1 11 DOTS entries: DT.99954967 DT.97840889 DT.100027352 DT.100785393 DT.91750056 DT.100671075 DT.92425569 DT.97843151 DT.99950019 DT.75199142 DT.99966454
 highest scoring ESTs for IAH1:AA042960 AA249311 AA482972 AA496151 AA524357 AA533526 AA553874 AA657408 AA683334 AA743945 Unigene Cluster for IAH1: Isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae) Hs.727610 [show with all ESTs]Unigene Representative Sequence: AK092982
GeneLoc Exon Structure
5/11 Alternative Splicing Database (ASD) splice patterns (SP) for IAH1 (see all 11)
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | · | 8c | · | 8d | ^ | 9 | ^ | 10a | · | 10b | · | 10c | · | 10d | · | 10e | · | 10f |
|---|
|
| SP1: | | | | | - | | - | | - | | - | | - | | - | | | | | | | | - | | | | | | | | | | - | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | - | | - | | - | | | | | | | | - | | | | | | | | | | - | | - | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | - | | - | | - | | - | | | | - | | | | - | | | | | | | | | | - | | - | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | - | | - | | | | | | | | - | | | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | - | | | | | | | | - | | | | | | | | | | - | | - | | | | | | | | | | | | | |
About this scheme
ECgene alternative splicing isoforms for IAH1
16 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000470914 ENST00000487850 ENST00000481688 ENST00000496603 ENST00000351760
ENST00000497473(uc002qzr.2 uc002qzs.2 uc002qzt.2) ENST00000495494
ENST00000481367(uc010yiz.1) ENST00000495050 ENST00000495797 ENST00000489468
ENST00000482918 ENST00000492223 ENST00000399109 ENST00000484826 ENST00000490621
|
Expression
for IAH1 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| IAH1 expression in normal and diseased human tissues
/ 2 / 3 4 probe-sets matching IAH1 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 225908_at2, 3
|
U133-B |
1 |
1.00 |
1.00 |
-- |
-- |
AI829927 |
0.60 |
1.00 |
0.82 |
1 |
| 230621_at2, 3
|
U133-B |
1 |
0.36 |
1.00 |
-- |
-- |
AA502936 |
0.40 |
1.00 |
0.76 |
1 |
| 225908_at2
|
U133Plus2 |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
| 230621_at2
|
U133Plus2 |
1 |
0.36 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: GTGCAGTACC
SOURCE GeneReport for Unigene cluster: Hs.727610
SABiosciences Custom PCR Arrays for IAH1
|
Orthologs
for IAH1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for IAH1 gene from 5/11 species (see all 11)
About this table Species with no ortholog for IAH1
ENSEMBL Gene Tree for IAH1 (if available) |
Paralogs
for IAH1 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| -- |
Genomic Variants
for IAH1 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
| | | QIAGEN SeqTarget long-range PCR primers for resequencing IAH1 |
|
Disorders & Mutations
for IAH1 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
IAH1 for disorders About GeneDecksing
OMIM: 602212
Export disorders and mutations for IAH1 gene to outside databases
|
Medical News
for IAH1 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for IAH1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
3 PubMed articles for IAH1 gene integrated from 7 sources:
(articles sorted by number of sources associating them with IAH1)- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
|
External Searches for IAH1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing IAH1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing IAH1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing IAH1 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for IAH1 gene:
Search GeneIP for patents involving IAH1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for IAH1 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
|
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| |  | Search Tocris compounds for IAH1 |
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