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PIGG Gene

protein-coding GIFtS: 48

GC04P000486

phosphatidylinositol glycan anchor biosynthesis, class G
(Previous names: phosphatidylinositol glycan, class G )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

		Products

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases & Descriptions
phosphatidylinositol glycan anchor biosynthesis, class G¹ ²		RLGS1930²
GPI7¹ ² ³		PRO4405²
phosphatidylinositol glycan, class G¹ ²		MGC131903²
LAS21¹ ²		DKFZp434M1131²
FLJ20265¹ ²		DKFZp434A1810²
Phosphatidylinositol-glycan biosynthesis class G protein² ³		FLJ39925²
PIG-G² ³		DKFZp434C1712²
hGPI7² ³		GPI ethanolamine phosphate transferase 2²
GPI7 homolog² ³		EC 2.-.-.-³
OTTHUMP00000216587²

External Ids:	HGNC: 25985¹	Entrez Gene: 54872²	Ensembl: ENSG00000174227⁷	UniProtKB: Q5H8A4³

Export aliases for PIGG gene to outside databases

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: PIGG_HUMAN, Q5H8A4

Function: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers

ethanolamine phosphate to the GPI second mannose

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the PIGG gene promoter:
         TBP   TFIID   CP1A   NF-YA   NF-Y   CP1C   FAC1   C/EBPalpha   c-Myb   CUTL1
         Other transcription factors

Search SABiosciences Chromatin IP Primers for PIGG

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for PIGG

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4p16.3 Ensembl cytogenetic band: 4p16.3 HGNC cytogenetic band: 4p16.3

PIGG Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PIGG gene location

GeneLoc gene densities for chromosome 4 GeneLoc Exon Structure

GeneLoc location for GC04P000486: view genomic region (about GC identifiers)

Start:	464,465 bp from pter
End:	533,985 bp from pter
Size:	69,521 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000004.11 NT_037622.5

(According to ¹UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: PIGG_HUMAN, Q5H8A4 (See protein sequence)

Recommended Name: GPI ethanolamine phosphate transferase 2

Size: 983 amino acids; 108173 Da

Subunit: Forms a complex with PIGF. PIGF is required to stabilize it. Competes with PIGO for the binding of PIGF

Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein

Sequence caution: Sequence=AAQ88902.1; Type=Erroneous termination; Positions=311; Note=Translated as Gln;

Sequence=BAA91046.1; Type=Erroneous initiation; Sequence=BAB55130.1; Type=Erroneous initiation;

Secondary accessions: Q2TAK5 Q6UX31 Q7L5Y4 Q8N866 Q8NCC9 Q96SY9 Q9BVT7 Q9NXG5

Alternative splicing: 5 isoforms: Q5H8A4-1 Q5H8A4-2 Q5H8A4-3 Q5H8A4-4 Q5H8A4-5

Explore the universe of human proteins at neXtProt for PIGG: NX_Q5H8A4

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (2 alternative transcripts):

NP_001120650.1 NP_060203.3

ENSEMBL proteins:

ENSP00000372494 ENSP00000426002 ENSP00000296306 ENSP00000422410 ENSP00000311750 ENSP00000427069

ENSP00000415203 ENSP00000423596 ENSP00000424800 ENSP00000424619 ENSP00000394941 ENSP00000421550

Human Recombinant Proteins

	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells Browse OriGene Protein Over-expression Lysates
	GenScript Custom Purified and Recombinant Proteins Services for PIGG
	Novus Biologicals Protein for PIGG
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins

4 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005783	endoplasmic reticulum	IDA	15632136
GO:0005789	endoplasmic reticulum membrane	EXP	15632136
GO:0016020	membrane	IEA	--
GO:0016021	integral to membrane	IEA	--

About this table

PIGG for ontologies About GeneDecksing

Antibodies for PIGG:

	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for PIGG
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies
	GenScript Custom Superior Antibodies Services for PIGG
	Browse antibodies at Epitomics

Assays for PIGG:

	Browse Kits and Assays available from Millipore
	Browse ELISAs at Sigma-Aldrich
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for PIGG
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for PIGG

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

PIGG for domains About GeneDecksing

3 InterPro domains/families:

IPR017849 Alkaline_Pase-like_a/b/a

IPR002591 Phosphodiest/P_Trfase

IPR017850 Alkaline_phosphatase_core

Graphical View of Domain Structure for InterPro Entry Q5H8A4

ProtoNet protein and cluster: Q5H8A4

UniProtKB/Swiss-Prot: PIGG_HUMAN, Q5H8A4

Similarity: Belongs to the PIGG/PIGN/PIGO family. PIGG subfamily

(According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
About This Section

UniProtKB/Swiss-Prot: PIGG_HUMAN, Q5H8A4

Function: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers

ethanolamine phosphate to the GPI second mannose

Enzyme Number (IUBMB): EC 2.-.-.-

Inhib. RNA:		Browse for Gene Knock-down Tools from Millipore
		Browse Nano Scale siRNA at Sigma-Aldrich Sigma-Aldrich esiRNA and siRNA for PIGG Sigma-Aldrich shRNA for PIGG
		OriGene 29mer shRNA kits in GFP-retroviral vector (see all 4): PIGG OriGene shRNA RFP (see all 4): PIGG OriGene basic RS shRNA (see all 4): PIGG OriGene siRNA (see all 2): PIGG
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of PIGG

miRNA:		Sigma-Aldrich microRNA Mimics for PIGG Sigma-Aldrich microRNA target validation systems for PIGG
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of PIGG
		Search SABiosciences for Assays for microRNAs that regulate PIGG

Gene
Editing:

Browse CompoZr Knockout ZFN at Sigma-Aldrich

Clones:		Browse Clones for the Expression of Recombinant Proteins Available from Millipore
		Browse iPSC Reprogramming Factors at Sigma-Aldrich
		OriGene GFP tagged cDNA clones in CMV expression vector: PIGG OriGene Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): PIGG OriGene untagged cDNA clones in CMV expression vector (see all 5): PIGG OriGene 3'-UTR clone (see all 2): PIGG Browse MicroRNA Expression Plasmids
		GenScript Custom cDNA clone Services for PIGG
		Browse Sino Biological Human cDNA Clones

Cell
Lines:

GenScript Custom overexpressing Cell Line Services for PIGG

5 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003824	catalytic activity	--	--
GO:0008484	sulfuric ester hydrolase activity	--	--
GO:0016740	transferase activity	IEA	--
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	EXP	15632136
GO:0051267	CP2 mannose-ethanolamine phosphotransferase activity	IDA	15632136

About this table

PIGG for ontologies About GeneDecksing

(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
About This Section

PIGG for pathways About GeneDecksing

3 Sigma-Aldrich "Your Favorite Gene" (powered by Ingenuity) Pathways for PIGG

	Glycerophospholipid Metabolism
	Aminophosphonate Metabolism
	Sphingolipid Metabolism

1 Kegg Pathway (Kegg details for PIGG):

hsa00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

UniProtKB/Swiss-Prot: PIGG_HUMAN, Q5H8A4

Pathway: Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis

    SABiosciences Custom Pathway-Focused PCR Arrays for PIGG

  Sigma-Aldrich "Your Favorite Gene" (powered by Ingenuity) Molecular Interaction Network for PIGG
  Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for PIGG

5/7 Interacting proteins for PIGG (ENSP00000372494³) via UniProtKB, MINT, and/or STRING (see all 7)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
GPAA1	ENSP00000347206³	STRING: ENSP00000347206
PIGK	ENSP00000359848³	STRING: ENSP00000359848
PIGO	ENSP00000339382³	STRING: ENSP00000339382
PIGS	ENSP00000309430³	STRING: ENSP00000309430
PIGT	ENSP00000279036³	STRING: ENSP00000279036

About this table

5/6 Gene Ontology (GO) biological process terms (GO ID links to tree view) (see all 6):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006501	C-terminal protein lipidation	TAS	--
GO:0006506	GPI anchor biosynthetic process	IDA	15632136
GO:0008152	metabolic process	--	--
GO:0016254	preassembly of GPI anchor in ER membrane	EXP	11102867
GO:0043687	post-translational protein modification	TAS	--

About this table

PIGG for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse Small Molecules at Sigma-Aldrich

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for PIGG

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore,
siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
About This Section

Inhib. RNA:		Browse for Gene Knock-down Tools from Millipore
		Browse Nano Scale siRNA at Sigma-Aldrich Sigma-Aldrich esiRNA and siRNA for PIGG Sigma-Aldrich shRNA for PIGG
		OriGene 29mer shRNA kits in GFP-retroviral vector (see all 4): PIGG OriGene shRNA RFP (see all 4): PIGG OriGene basic RS shRNA (see all 4): PIGG OriGene siRNA (see all 2): PIGG
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of PIGG

miRNA:		Sigma-Aldrich microRNA Mimics for PIGG Sigma-Aldrich microRNA target validation systems for PIGG
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of PIGG
		Search SABiosciences for Assays for microRNAs that regulate PIGG

Clones:		Browse FLAG tag genes at Sigma-Aldrich
		OriGene GFP tagged cDNA clones in CMV expression vector: PIGG OriGene Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): PIGG OriGene untagged cDNA clones in CMV expression vector (see all 5): PIGG OriGene 3'-UTR Clone (see all 2): PIGG Browse OriGene MicroRNA Expression Plasmids
		GenScript Custom cDNA clone Services for PIGG

Primers:		OriGene genome-wide validated SYBR primer pairs: PIGG Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay for PIGG: PPH07474A

REFSEQ mRNAs for PIGG gene (2 alternative transcripts):

NM_001127178.1 NM_017733.3

Additional cDNA sequence:

AB162713.1 AK000272.1 AK027465.1 AK074715.1 AK074815.1 AK097244.1 AK124537.1 AK296507.1

AK309107.1 AL137741.1 AL162084.1 AY358538.1 BC000937.2 BC001249.1 BC050262.1 BC110878.1

BC144576.1 CR619317.1

24/25 DOTS entries (see all 25):

DT.91928988 DT.411539 DT.213084 DT.100775750 DT.425388 DT.91746356 DT.100745115 DT.40276263

DT.121227532 DT.102831542 DT.100044190 DT.86846644 DT.97768962 DT.86856239 DT.91986634 DT.95356170

DT.102831543 DT.121227452 DT.121227486 DT.121227547 DT.40130531 DT.95147745 DT.97789776 DT.91954556

24/161 AceView cDNA sequences (see all 161):

AW268135 AK097244 BQ774237 F02060 AW614790 AI471556 AI560517 BM455257

CR619317 Z41088 AK074715 BE440149 BC000937 AW239182 BQ001548 BU634386

AK000272 CK300616 BC001249 BU191836 AL698226 BM831504 CA397074 AL162084

highest scoring ESTs for PIGG:

AI089774 AA455090 AA703436 AA935093 AA937505 AI281604 AI337875 AI363093 AI376876 AI750006

Unigene Cluster for PIGG:

Phosphatidylinositol glycan anchor biosynthesis, class G

Hs.7099 [show with all ESTs]

Unigene Representative Sequence: AK124537

GeneLoc Exon Structure

5/18 Alternative Splicing Database (ASD) splice patterns (SP) for PIGG (see all 18)

ExUns:	1a	·	1b	·	1c	·	1d	·	1e	^	2a	·	2b	·	2c	^	3a	·	3b	^	4	^	5	^	6	^	7	^	8	^	9a	·	9b	·	9c	^	10a	·	10b	·	10c	·	10d	^	11	^	12	^	13a	·	13b	·
SP1:													-		-						-		-																				-						-		-
SP2:													-		-						-		-																										-		-
SP3:											-		-		-						-		-																										-		-
SP4:													-		-						-		-																-		-		-				-
SP5:																					-		-

ExUns:	13c	·	13d	^	14a	·	14b	^	15a	·	15b	·	15c	^	16a	·	16b	·	16c	^	17a	·	17b	·	17c	^	18a	·	18b	^	19a	·	19b	^	20a	·	20b
SP1:	-		-						-		-		-		-				-								-		-
SP2:	-		-						-		-		-		-				-								-		-
SP3:	-		-						-		-		-		-				-								-		-
SP4:
SP5:

About this scheme

ECgene alternative splicing isoforms for PIGG
18/29 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 29):

ENST00000383028 ENST00000502311 ENST00000503111(uc003gam.2) ENST00000515237

ENST00000507493 ENST00000506898 ENST00000514953 ENST00000508669 ENST00000296306

ENST00000513192 ENST00000510235 ENST00000503261 ENST00000310340(uc003gaj.3)

ENST00000513239 ENST00000511247 ENST00000504187 ENST00000515624 ENST00000453061(uc003gak.3 uc010ibf.2 uc003gal.3)

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Primers from OriGene and/or SABiosciences )
About This Section

PIGG expression in normal and diseased human tissues

¹ / ² / ³

5 probe-sets matching PIGG gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
67530_at²^{, 3}	U95-D	1	1.00	1.00	0.84	0.89	AI521101	0.60	1.00	0.82	1
54124_at²^{, 3}	U95-B	1	1.00	1.00	0.94	1.11	AI089774	1.00	1.00	1.00	1
218652_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_017733	0.60	1.00	0.82	1
218652_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
1563842_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

PIGG for expression About GeneDecksing

Data from Genenote (Publications) and GNF BioGPS
About these images

PIGG gene electronic northern expression

About these images

CGAP SAGE TAG: CTTAAAGTCT

SOURCE GeneReport for Unigene cluster: Hs.7099

Primers:		OriGene genome-wide validated SYBR primer pairs: PIGG Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay for PIGG: PPH07474A

SABiosciences Custom PCR Arrays for PIGG

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for PIGG gene from 5/14 species (see all 14)

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	PIGG¹	--	phosphatidylinositol glycan anchor biosynthesis, class more	83.61(n) 83.71(a)	479136 XM_536282.2 XP_536282.2
chimpanzee (Pan troglodytes)	PIGG¹	--	phosphatidylinositol glycan anchor biosynthesis, class more	99.28(n) 99.28(a)	461039 XM_001138024.1 XP_001138024.1
rat (Rattus norvegicus)	Pigg¹	--	phosphatidylinositol glycan anchor biosynthesis, class more	80.88(n) 81.26(a)	305626 XM_223731.4 XP_223731.4
mouse (Mus musculus)	Pigg^{1 , 5}	5 (52.90 cM)⁵	phosphatidylinositol glycan anchor biosynthesis, class more^{1, 5}	81.13(n)¹ 80.82(a)¹	433931¹ NM_001081234.1¹ NP_001074703.1¹ BC051059⁵
chicken (Gallus gallus)	PIGG¹	--	phosphatidylinositol glycan anchor biosynthesis, class more	70.87(n) 71.77(a)	427290 XM_424872.2 XP_424872.2

About this table Species with no ortholog for PIGG

ENSEMBL Gene Tree for PIGG (if available)

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(SNPs according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section

SNP ID	Valid	Chr 4 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
Genomic Data				Transcription Related Data				Allele Frequencies
			--	--	--		--	--
rs1127410^1,2	C,F,O,A,	533001(+)	`AGTTTT/CCACGT`	4	/S /F	mis¹ ref¹ ese³		29		MN EA NA NS WA	2312
rs1135945^1,2	C,F,A,	516586(+)	`TGCACG/ACAGTA`	2	--	int¹		21		EA NA NS WA	1450
rs1867188^1,2	C,F,A,	504012(-)	`tagaaC/Acaatg`	2	--	int¹		8		NS EA	836
rs2289595^1,2	C,F,	500609(-)	`TCTACA/CTGTGT`	2	--	int¹		6		EA NS	1968
rs2304915^1,2	F,H	499805(-)	`TAAAAT/GGGTAT`	2	--	int¹		3		EA NS	1634
rs3211083^1,2	C,A,	526848(+)	`TGCGCG/AGAGAG`	2	--	int¹ ese³		4		NS NA WA	196
rs3211084^1,2	--	526974(+)	`CTGGCC/AAGAAC`	2	--	int¹ ese³		1		MN	184
rs3211085^1,2	--	527595(+)	`CTTCTC/TCTATT`	2	--	int¹ ese³ trp³		0	--	--	--	--
rs4130382^1,2	C,F,	509178(-)	`TAAAGC/TTCAAG`	2	--	int¹		11		NA NS EA	976
rs4259011^1,2	--	526668(+)	`GGAGGA/CGGGGC`	2	--	int¹		0	--	--	--	--

About this table

HapMap Linkage Disequilibrium images for PIGG (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for PIGG: --

QIAGEN SeqTarget long-range PCR primers for resequencing PIGG

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
About This Section

PIGG for disorders About GeneDecksing

Human Genome Epidemiology (HuGE) Navigator: PIGG (3 documents)

Export disorders and mutations for PIGG gene to outside databases

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶UniProtKB/TrEMBL, and/or ⁷Novoseek)
About This Section

10/11 PubMed articles for PIGG gene, integrated from 7 sources (see all 11):
(articles sorted by number of sources associating them with PIGG)

GPI7 is the second partner of PIG-F and involved in modification of glycosylphosphatidylinositol. (PubMed id 15632136)^{1, 2, 3} Shishioh N.... Kinoshita T. (2005)
Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)^{1, 2} Otsuki T....Isogai T. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)^{1, 2} Clark H.F.... Gray A.M. (2003)
Assessment of a polymorphism of SDK1 with hypertensio n in Japanese Individuals. (PubMed id 19851296)¹ Oguri M....Yamada Y. (2010)
Association of genetic variants with hemorrhagic stro ke in Japanese individuals. (PubMed id 20198315)¹ Yoshida T....Yamada Y. (2010)
Association of gene polymorphisms with chronic kidney disease in Japanese individuals. (PubMed id 19724895)¹ Yoshida T....Yamada Y. (2009)
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)¹ Kimura K.... Sugano S. (2006)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 54872	HGNC: 25985	AceView: FLJ20265	Ensembl:ENSG00000174227	euGenes: HUgn54872
ECgene: PIGG	Kegg: 54872	H-InvDB: PIGG

(According to HUGE)
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(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Intellectual Property for PIGG gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from XenneX, Inc.)

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Patent Information for PIGG gene:
Search GeneIP for patents involving PIGG

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protein-coding GIFtS: 48

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PIGG (Gene Symbol)
phosphatidylinositol glycan anchor biosynthesis, class G
GPI7
phosphatidylinositol glycan, class G
LAS21
FLJ20265
Phosphatidylinositol-glycan biosynthesis class G protein
PIG-G
hGPI7
GPI7 homolog
OTTHUMP00000216587
RLGS1930
PRO4405
MGC131903
DKFZp434M1131
DKFZp434A1810
FLJ39925
DKFZp434C1712
GPI ethanolamine phosphate transferase 2
EC 2.-.-.-

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PIGG Gene

protein-coding GIFtS: 48

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