Aliases & Descriptions for POTEA gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| Aliases & Descriptions |
|---|
| POTE ankyrin domain family, member A1 2 | | A26A12 3 | | POTE81 2 3 | | ANKRD26-like family A member 12 3 | | POTE-81 2 3 | | POTE ankyrin domain family member A2 | | ANKRD26-like family A, member 11 2 | | cancer/testis antigen family 104, member 32 | | CT104.31 2 | | protein expressed in prostate, ovary, testis, and placenta 82 | | Prostate, ovary, testis-expressed protein on chromosome 82 3 | | |
Export aliases for POTEA gene to outside databasesPrevious GC identifers: GC08P043268 GC08P043147 |
Summaries for POTEA gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| -- |
Genomic Views for POTEA gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences) About This Section
| Regulatory elements: Search SABiosciences Regulatory transcription factor binding sites for POTEA Other transcription factors
Search SABiosciences Chromatin IP Primers for POTEA
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays  |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 8p11.1 Ensembl cytogenetic band: 8p11.1 HGNC cytogenetic band: 8p11.1POTEA Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 8 GeneLoc Exon Structure GeneLoc location for GC08P041671: view genomic region
(about GC identifiers)
Start:
|
41,671,733 bp from pter |
End:
|
41,742,486 bp from pter |
Size:
|
70,754 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr8+ 43,147,585-43,218,328 |
RefSeq DNA sequence:- NC_000008.10 NT_167187.1
|
Proteins for POTEA gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
| UniProtKB/Swiss-Prot: POTEA_HUMAN, Q6S8J7 (See
protein sequence)Recommended Name: POTE ankyrin domain family member A Size: 498 amino acids; 56166 Da
Secondary accessions: A6ND17 A6ND71 Q6S8J6Alternative splicing: 2 isoforms: Q6S8J7-1 Q6S8J7-2 Explore the universe of human proteins at neXtProt for POTEA: NX_Q6S8J7 
REFSEQ proteins (2 alternative transcripts):
NP_001002920.1 NP_001005365.2 Human Recombinant Proteins
Antibodies for POTEA: Assays for POTEA: |
Protein
Domains/ Families for POTEA gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
POTEA for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q6S8J7ProtoNet protein and cluster: Q6S8J7 1 Blocks protein family: IPB002110 Ankyrin repeat signature
UniProtKB/Swiss-Prot: POTEA_HUMAN, Q6S8J7Similarity: Belongs to the POTE familySimilarity: Contains 5 ANK repeats |
Gene Function for POTEA gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
|
Pathways & Interactions for POTEA gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
| SABiosciences Custom Pathway-Focused PCR Arrays for POTEA 
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for POTEA
|
Drugs & Compounds for POTEA gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
Browse Tocris compounds for POTEA
|
Transcripts for POTEA gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences) About This Section
|
REFSEQ mRNAs for POTEA gene (2 alternative transcripts): NM_001002920.1 NM_001005365.2 Additional cDNA sequence: AY462869.1 AY462870.1 2 DOTS entries: DT.102826485 DT.102826537 3 AceView cDNA sequences: AY462869 AY462870 NM_001002920 Unigene Cluster for POTEA: POTE ankyrin domain family, member A Hs.531579 Unigene Representative Sequence: AY462869
GeneLoc Exon Structure
2 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000522175 ENST00000519951
|
Expression for POTEA gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| POTEA expression in normal and diseased human tissues
1 Data from GNF BioGPS About these images
About these images
CGAP SAGE TAG: CTAAGAATAG
SOURCE GeneReport for Unigene cluster: Hs.531579 SABiosciences Custom PCR Arrays for POTEA 
|
Orthologs for POTEA gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for POTEA gene from 1 species
| Organism |
Gene |
Locus |
Description |
Human Similarity |
NCBI accessions |
chimpanzee (Pan troglodytes) |
POTEA1 |
-- |
POTE ankyrin domain family, member A |
98.93(n) 97.99(a) |
472754 XM_001140309.1 XP_001140309.1 |
About this table Species with no ortholog for POTEA
ENSEMBL Gene Tree for POTEA (if available) |
Paralogs for POTEA gene(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| -- |
Genomic Variants for POTEA gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 8 pos | Sequence | Recs | AA Chg | Type | More | Recs | Allele freq | Pop | Total sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for POTEA (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 7 variations for POTEA 6 CNVs: 53780 29790 29791 59477 95398 52536 1 Indel: 47541 |  | QIAGEN SeqTarget long-range PCR primers for resequencing POTEA  |
|
Disorders & Mutations for POTEA gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
POTEA for disorders About GeneDecksing
OMIM: 608915
Export disorders and mutations for POTEA gene to outside databases
|
Medical News for POTEA gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for POTEA gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
| 4 PubMed articles for POTEA gene integrated from 7 sources: (articles sorted by number of sources associating them with POTEA)- Five POTE paralogs and their splice variants are expressed in human prostate and encode proteins of different lengths. (PubMed id 15276201)1, 2 Bera T.K.... Pastan I. (2004)
- Duplication and extensive remodeling shaped POTE family genes encoding proteins containing ankyrin repeat and coiled coil domains. (PubMed id 16364570)1 Hahn Y.... Lee B. (2006)
- DNA sequence and analysis of human chromosome 8. (PubMed id 16421571)2 Nusbaum C....Lander E.S. (2006)
- POTE, a highly homologous gene family located on numerous chromosomes and expressed in prostate, ovary, testis, placenta, and prostate cancer. (PubMed id 12475935)1 Bera T.K.... Pastan I. (2002)
|
External Searches for POTEA gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing POTEA gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing POTEA gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing POTEA gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
|
About This Section
| Patent Information for POTEA gene: Search GeneIP for patents involving POTEA
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for POTEA gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn, Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences) About This Section
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| | | Search Tocris compounds for POTEA |
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 | | ELISAs and CLIAs for POTEA |
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