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TMEM85 Gene

protein-coding   GIFtS: 45

GC15P011380
transmembrane protein 85
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases & Descriptions
transmembrane protein 851 2
MGC244151 2
FLJ907461 2
PIG171 2
Cell proliferation-inducing gene 17 protein2 3
proliferation-inducing gene 172

External Ids:    HGNC: 280321   Entrez Gene: 512342   Ensembl: ENSG000001284637   UniProtKB: Q5J8M33   

Export aliases for TMEM85 gene to outside databases

Previous GC identifers: GC15P032305 GC15P034517


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: TMM85_HUMAN, Q5J8M3
Function: May mediate anti-apoptotic activity


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TMEM85 gene promoter:
         Bach1   FOXO3b   FOXO3a   c-Myb   Elk-1   FOXO4   POU3F2 (N-Oct-5b)   POU3F2 (N-Oct-5a)   POU3F2   Nkx2-2   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for TMEM85

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q14   Ensembl cytogenetic band:  15q14   HGNC cytogenetic band: 15q14

TMEM85 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM85 gene location

GeneLoc gene densities for chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15P011380:  view genomic region     (about GC identifiers)

Start:
11,380,729 bp from pter
End:
11,385,840 bp from pter
Size:
5,112 bases
Orientation:
plus strand

1 alternative location:
Chr15+ 34,517,200-34,522,357     
RefSeq DNA sequence:
NC_000015.9  NT_010194.17  

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: TMM85_HUMAN, Q5J8M3 (See protein sequence)
Recommended Name: Transmembrane protein 85  
Size: 183 amino acids; 20087 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Secondary accessions: A8K3A9 B4DJQ4 Q96KX9 Q9BUI5 Q9P0T9
Alternative splicing: 3 isoforms:  Q5J8M3-1   Q5J8M3-2   Q5J8M3-3   

Explore the universe of human proteins at neXtProt for TMEM85: NX_Q5J8M3 

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins: NP_057538.1  

    ENSEMBL proteins: 
    ENSP00000267750 ENSP00000249209 ENSP00000389301 


    Human Recombinant Proteins 
    Browse Purified and Recombinant Proteins at Millipore
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    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate: TMEM85
    GenScript Custom Purified and Recombinant Proteins Services for TMEM85 
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins

    2 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016020 membrane IEA--
    GO:0016021 integral to membrane IEA--
    About this table

    TMEM85 for ontologies           About GeneDecksing



    Antibodies for TMEM85: 
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    Browse antibodies at Epitomics

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    Browse Kits and Assays available from Millipore
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    GenScript Custom Assay Services for TMEM85 
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs and CLIAs at Uscn 


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TMEM85 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR009445 DUF1077_TMEM85

    Graphical View of Domain Structure for InterPro Entry Q5J8M3

    ProtoNet protein and cluster: Q5J8M3

    UniProtKB/Swiss-Prot: TMM85_HUMAN, Q5J8M3
    Similarity: Belongs to the TMEM85 family


    (According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
    About This Section

    UniProtKB/Swiss-Prot: TMM85_HUMAN, Q5J8M3
    Function: May mediate anti-apoptotic activity

    Inhib.
    RNA:
        
    Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich esiRNA and siRNA for TMEM85
    Sigma-Aldrich shRNA for TMEM85
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): TMEM85
    OriGene shRNA RFP (see all 2): TMEM85
    OriGene basic RS shRNA (see all 2): TMEM85
    OriGene siRNA (see all 2): TMEM85
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of TMEM85 
    miRNA:Sigma-Aldrich microRNA Mimics for TMEM85
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of TMEM85 
    8/9 SABiosciences Assays for microRNAs that regulate TMEM85 (see all 9):
    hsa-miR-142-5p hsa-miR-15a hsa-miR-561 hsa-miR-488 hsa-miR-497 hsa-miR-424 hsa-miR-16 hsa-miR-195

    Gene
    Editing:
    Browse CompoZr Knockout ZFN at Sigma-Aldrich 

    Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
    Browse iPSC Reprogramming Factors at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: TMEM85
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: TMEM85
    OriGene untagged cDNA clones in CMV expression vector (see all 2): TMEM85
    OriGene 3'-UTR clone: TMEM85 
    Browse MicroRNA Expression Plasmids 
    GenScript cDNA clone with any tag delivered in your preferred vector: TMEM85 
    Browse Sino Biological Human cDNA Clones

    Cell
    Lines:
      
    GenScript Custom overexpressing Cell Line Services for TMEM85 


    (Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
    About This Section

        SABiosciences Custom Pathway-Focused PCR Arrays for TMEM85 

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TMEM85

    1 Gene Ontology (GO) biological process term (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006915 apoptosis IEA--
    About this table

    TMEM85 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section
    Browse Small Molecules at Sigma-Aldrich
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TMEM85


    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Millipore,
    siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
    Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
    About This Section

    Inhib.
    RNA:
         
    Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich esiRNA and siRNA for TMEM85
    Sigma-Aldrich shRNA for TMEM85
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): TMEM85
    OriGene shRNA RFP (see all 2): TMEM85
    OriGene basic RS shRNA (see all 2): TMEM85
    OriGene siRNA (see all 2): TMEM85
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of TMEM85 
    miRNA: Sigma-Aldrich microRNA Mimics for TMEM85
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of TMEM85 
    8/9 SABiosciences Assays for microRNAs that regulate TMEM85 (see all 9):
    hsa-miR-142-5p hsa-miR-15a hsa-miR-561 hsa-miR-488 hsa-miR-497 hsa-miR-424 hsa-miR-16 hsa-miR-195
    Clones: Browse FLAG tag genes at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: TMEM85
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: TMEM85
    OriGene untagged cDNA clones in CMV expression vector (see all 2): TMEM85
    OriGene 3'-UTR Clone: TMEM85 
    Browse OriGene MicroRNA Expression Plasmids 
    GenScript cDNA clone with any tag delivered in your preferred vector: TMEM85 
    Primers: OriGene genome-wide validated SYBR primer pairs: TMEM85
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for TMEM85: PPH15099A

    REFSEQ mRNAs for TMEM85 gene: 

    NM_016454.2  

    Additional cDNA sequence: 

    AF151018.1 AK075227.1 AK091678.1 AK290524.1 AK296184.1 AY336092.1 BC002583.2 BC016348.1 
    CR595333.1 CR597763.1 CR597809.1 CR599971.1 CR607532.1 CR609616.1 CR619572.1 CR620239.1 

    16 DOTS entries:

    DT.453348  DT.100658956  DT.92439651  DT.99998399  DT.91665380  DT.100658962  DT.211584  DT.429427 
    DT.97862185  DT.100658960  DT.92016474  DT.100038951  DT.121056296  DT.95096912  DT.95134332  DT.101976770 

    24/540 AceView cDNA sequences (see all 540):

    BP430002 CA952828 CA446561 BM695554 CA748824 AI188254 AW008691 AI051928 
    NM_016454 BM794739 BM973408 CB853618 CR607532 CB218966 CB108608 BM787144 
    BM749490 AA631880 AI350819 BU078680 CA848336 BM703567 BU539347 CF128016 

    highest scoring ESTs for TMEM85:

    AI887986 AA036893 AA127482 AA146840 AA196875 AA334127 AA372234 AA513745 AA631880 AA772681 

    Unigene Cluster for TMEM85:

    Transmembrane protein 85
    Hs.250905  [show with all ESTs]
    Unigene Representative Sequence: AK091678


    GeneLoc Exon Structure

    5/10 Alternative Splicing Database (ASD) splice patterns (SP) for TMEM85 (see all 10)

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c · 2d ^ 3a · 3b · 3c ^ 4a · 4b · 4c · 4d ^ 5 ^ 6a · 6b · 6c · 6d · 6e
    SP1:                                -     -                 -     -                 -     -                                 
    SP2:                                      -                 -     -                 -     -                                 
    SP3:                                -     -                 -     -     -     -     -     -                                 
    SP4:                    -           -     -                 -     -                                                         
    SP5:                                -     -           -     -     -     -     -     -                                       

    About this scheme

    ECgene alternative splicing isoforms for TMEM85
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000267750(uc001zhq.2 uc001zhr.2 uc001zhs.2 uc010bat.2)
    ENST00000249209 ENST00000416323(uc010ucb.1)

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Primers from OriGene and/or SABiosciences )
    About This Section

    TMEM85 expression in normal and diseased human tissues

    1  / 2  / 3

    6 probe-sets matching TMEM85 gene

    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    80562_s_at2, 3 U95-E 1 1.00 1.00 0.94 1.08 AI969465 0.80 1.00 0.91 1
    49175_at2, 3 U95-C 1 0.75 1.00 0.96 0.92 AI887986 1.00 1.00 1.00 1
    223857_x_at2, 3 U133-B 1 1.00 1.00 -- -- BC002583 0.80 1.00 0.91 1
    223043_at2, 3 U133-B 1 0.82 1.00 -- -- AF151018 0.80 1.00 0.91 1
    223857_x_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    223043_at2 U133Plus2 1 0.82 1.00 -- -- -- -- -- -- --
    About this table

    TMEM85 for expression           About GeneDecksing

    Data from Genenote  (Publications) and GNF BioGPS
        About these images
    TMEM85 gene expression
    TMEM85 gene electronic northern expression
    TMEM85 gene sage expression
    About these images

    CGAP SAGE TAG: GTGGGGTGAC

    SOURCE GeneReport for Unigene cluster: Hs.250905

    UniProtKB/Swiss-Prot: TMM85_HUMAN, Q5J8M3
    Tissue specificity: Isoform 1 is expressed in brain and heart. Isoform 2 is expressed in heart

    Primers: OriGene genome-wide validated SYBR primer pairs: TMEM85
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for TMEM85: PPH15099A
        SABiosciences Custom PCR Arrays for TMEM85 


    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section

    Orthologs for TMEM85 gene from 5/14 species (see all 14)
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    dog
    (Canis familiaris)
    TMEM851   -- transmembrane protein 85 94.17(n)
    97.81(a)
    478241  XM_535416.2  XP_535416.1 
    chimpanzee
    (Pan troglodytes)
    TMEM851   -- transmembrane protein 85 96.9(n)
    94.54(a)
    453300  XM_510280.2  XP_510280.2 
    cow
    (Bos taurus)
    TMEM851   -- transmembrane protein 85 94.72(n)
    98.91(a)
    523162  NM_001034547.1  NP_001029719.1 
    rat
    (Rattus norvegicus)
    Tmem851   -- transmembrane protein 85 92.17(n)
    97.81(a)
    296049  XM_215797.4  XP_215797.4 
    mouse
    (Mus musculus)
    Tmem851 , 5 2 (57.02 cM)5
    transmembrane protein 851, 5 93.44(n)1
    99.45(a)1
    680321  NM_026519.21  NP_080795.11 
     AI8499615  AK0036685  (see all 9)
    About this table        Species with no ortholog for TMEM85

    ENSEMBL Gene Tree for TMEM85 (if available)

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section
      --

    (SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
    About This Section

    10/89 NCBI SNPs in TMEM85 are shown (see all 89)
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidChr 15 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ----------
    rs11328691,2
    --34517337(+) CTGTGG/TTGGCT 2 V L ref1 mis10--------
    rs27051051,2
    H34520802(+) CAAAAG/AAAAAG 1 -- int1 trp34Minor allele frequency- A:0.00NS EA 418
    rs27051161,2
    --34516746(+) tttgaA/Gacaga 1 -- ng510--------
    rs27053281,2
    C34516711(+) GTTAAG/AAAGCT 1 -- ng514Minor allele frequency- A:0.00NS EA 416
    rs71652801,2
    C34521181(+) actgcG/Acctgg 1 -- int12Minor allele frequency- A:0.50NA 4
    rs71675031,2
    C,H34521253(+) taattT/Aattta 1 -- int14Minor allele frequency- A:0.00NA 12
    rs80359541,2
    C,F,A,H,34519563(+) tggatG/Ttatct 1 -- int113Minor allele frequency- T:0.42NS EA NA WA 644
    rs80406471,2
    C,F,34517696(+) GAAGTA/GTCGGA 1 -- int15Minor allele frequency- G:0.03NS EA WA 466
    rs115444331,2
    --34519923(+) CCCCTA/CAAACA 2 L syn1 ref1 ese30--------
    rs115444341,2
    H34519942(-) GAAGAG/AATTCA 2 /L /F ref1 mis1 ese34Minor allele frequency- A:0.00NS EA 404
    About this table

    HapMap Linkage Disequilibrium images for TMEM85 (up to first 250kb)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for TMEM85
         1 CNV: 7058

    QIAGEN SeqTarget long-range PCR primers for resequencing TMEM85 

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
      --

    (Possibly Related Articles in Doctor's Guide)
    About This Section
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
    About This Section

    8 PubMed articles for TMEM85 gene integrated from 7 sources:
    (articles sorted by number of sources associating them with TMEM85)
    1. Transmembrane protein 85 from both human (TMEM85) and yeast (YGL231c) inhibit hydrogen peroxide mediated cell death in yeast. (PubMed id 18586032)1, 2, 7 Ring G....Greenwood M.T. (2008)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (2000)
    5. Analysis of the DNA sequence and duplication history of human chromosome 15. (PubMed id 16572171)2 Zody M.C....Nusbaum C. (2006)
    6. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1 Otsuki T....Isogai T. (2005)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    8. Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51234 HGNC: 28032 AceView: LOC51234 Ensembl:ENSG00000128463 euGenes: HUgn51234
    ECgene: TMEM85 H-InvDB: TMEM85

    (According to HUGE)
    About This Section
      --

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
      --

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from XenneX, Inc.)
    About This Section
    Patent Information for TMEM85 gene:
    Search GeneIP for patents involving TMEM85

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
    Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
    About This Section

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services

     Predesigned and custom siRNAs for TMEM85 Browse antibodies at Sigma-Aldrich
     Super-pooled esiRNAs for TMEM85 Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for TMEM85 microRNA Mimics for TMEM85
     "Your Favorite Gene" Pathways and Molecular Interaction Networks Browse Nano Scale siRNA at Sigma-Aldrich
     Browse iPSC Reprogramming Factors at Sigma-Aldrich Browse small molecules at Sigma-Aldrich
     Browse FLAG tag genes at Sigma-Aldrich Browse ELISAs at Sigma-Aldrich
     Browse microRNA Target Validation Systems at Sigma-Aldrich Browse CompoZr Knockout ZFN at Sigma-Aldrich
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     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of TMEM85
     SeqTarget long-range PCR primers for resequencing TMEM85
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of TMEM85
     GenScript Custom Purified and Recombinant Proteins Services for TMEM85 GenScript cDNA clones with any tag delivered in your preferred vector for TMEM85
     GenScript Custom Assay Services for TMEM85 GenScript Custom Superior Antibodies Services for TMEM85
     GenScript Custom overexpressing Cell Line Services for TMEM85 CloneReady with Over 120,000 Genes
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