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Aliases & Descriptionsfor ZNF226 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc
, and/or 7 Ensembl ,
8 miRBase )About This Section Aliases & Descriptions zinc finger protein 2261 2 Kruppel-associated box protein2
Export aliases for ZNF226 gene to outside databases Previous GC identifers: GC19P045314 GC19P045060 GC19P049345 GC19P049361 GC19P049355 GC19P044669
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Summariesfor ZNF226 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section UniProtKB/Swiss-Prot: ZN226_HUMAN, Q9NYT6 Function : May be involved in transcriptional regulation
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Genomic Viewsfor ZNF226 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60) ,
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences )About This Section Regulatory elements: Search SABiosciences Regulatory transcription factor binding sites for ZNF226 Other transcription factors Search SABiosciences Chromatin IP Primers for ZNF226 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 19q13.2 Ensembl cytogenetic band: 19q13.31 HGNC cytogenetic band: 19q13.2 ZNF226 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc gene densities for chromosome 19 GeneLoc Exon Structure
GeneLoc location for GC19P041101: view genomic region
(about GC identifiers )
Start:
41,101,354 bp from pter
End:
41,113,971 bp from pter
Size:
12,618 bases
Orientation:
plus strand
1 alternative location : Chr 19+ 44,669,249-44,681,836
RefSeq DNA sequence: NC_000019.9 NT_011109.16
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Proteinsfor ZNF226 gene
(According to
1 UniProtKB ,
neXtProt ,
and/or Ensembl ,
Phosphorylation sites according to 2 Phosphosite ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological , and/or
ProSpec ,
Biochemical Assays by
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene ,
Antibodies by
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals , and/or
Epitomics )
About This Section UniProtKB/Swiss-Prot: ZN226_HUMAN, Q9NYT6 (See
protein sequence )Recommended Name: Zinc finger protein 226 Size : 803 amino acids; 91921 Da
Subcellular location : Nucleus (Probable)
Secondary accessions : Q96TE6 Q9NS44Explore the universe of human proteins at neXtProt for ZNF226: NX_Q9NYT6 Post-translational modifications:
View phosphorylation sites using PhosphoSite 2
REFSEQ proteins (5 alternative transcripts):
NP_001027544.1 NP_001027545.1 NP_001027546.1 NP_001139692.1 NP_057003.2 ENSEMBL proteins: ENSP00000336719 ENSP00000393265 ENSP00000407474 ENSP00000300823 Human Recombinant Proteins 2 Gene Ontology (GO) cellular component terms (GO ID links to tree view) :
About this table
ZNF226 for ontologies About GeneDecksing Antibodies for ZNF226: Assays for ZNF226:
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Protein
Domains/ Familiesfor ZNF226 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
ZNF226 for domains About GeneDecksing 4 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry Q9NYT6 ProtoNet protein and cluster: Q9NYT6
1 Blocks protein family : IPB001909 KRAB box UniProtKB/Swiss-Prot: ZN226_HUMAN, Q9NYT6 Similarity : Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity : Contains 19 C2H2-type zinc fingersSimilarity : Contains 1 KRAB domain
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Gene Functionfor ZNF226 gene
(According to UniProtKB ,
IUBMB ,and/or
Genatlas , Animal models from MGI Dec 24 2010,
shRNA from
OriGene ,
Sigma-Aldrich ,
RNAi from
Millipore ,
siRNAs from
Sigma-Aldrich ,
OriGene ,
Qiagen ,
Super-pooled esiRNAs from Sigma-Aldrich ,
microRNA from Sigma-Aldrich ,
Qiagen ,
SABiosciences ,
Clones from Millipore ,
Sigma-Aldrich ,
OriGene ,
GenScript ,
Sino Biological ,
Cell Lines from GenScript ,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene .)
About This Section UniProtKB/Swiss-Prot: ZN226_HUMAN, Q9NYT6 Function : May be involved in transcriptional regulation
4 Gene Ontology (GO) molecular function terms (GO ID links to tree view) :
About this table
ZNF226 for ontologies About GeneDecksing
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Pathways & Interactionsfor ZNF226 gene
(Pathways according to
Millipore ,
Cell Signaling Technology ,
Sigma-Aldrich ,
KEGG
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
PCR Arrays from
SABiosciences ,
Proteins Network according to
SABiosciences ,
Sigma-Aldrich ,
Interactions according to 1 UniProtKB ,
2 MINT , and/or
3 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene) .
About This Section SABiosciences Custom Pathway-Focused PCR Arrays for ZNF226 Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF226 1 Gene Ontology (GO) biological process term (GO ID links to tree view) :
GO ID Qualified GO term Evidence PubMed IDs GO:0006355 regulation of transcription, DNA-dependent
IEA --
About this table
ZNF226 for ontologies About GeneDecksing
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Drugs & Compoundsfor ZNF226 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
Sigma-Aldrich , Tocris Bioscience , and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB )
About This Section Browse Tocris compounds for ZNF226
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Transcriptsfor ZNF226 gene (GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
non coding RNAs according to
RNAdb ,
ESTs according to GeneTide ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
Millipore ,
siRNAs from
Sigma-Aldrich ,
OriGene ,
Qiagen ,
Super-pooled esiRNAs from Sigma-Aldrich ,
shRNA from
Sigma-Aldrich ,
OriGene ,
microRNA from Sigma-Aldrich ,
Qiagen ,
SABiosciences ,
Tagged/untagged cDNA clones from
OriGene ,
Sigma-Aldrich ,
GenScript ,
Primers from
OriGene and/or
SABiosciences )About This Section REFSEQ mRNAs for ZNF226 gene (5 alternative transcripts): NM_001032372.1 NM_001032373.1 NM_001032374.1 NM_001146220.2 NM_015919.3
Additional cDNA sequence: AF024707.1 AF070666.1 AF228418.1 AF246126.1 AK023091.1 AK314554.1 AK314724.1 BC017786.1 BC024197.2 BX537487.1 BX648775.1
19 DOTS entries : DT.97797676 DT.99938400 DT.313520 DT.313519 DT.92424715 DT.92424718 DT.121501486 DT.449852
DT.121501509 DT.95235040 DT.102834840 DT.313521 DT.40111006 DT.95235039 DT.100694546 DT.121501494 DT.95231456 DT.95266386 DT.95328520 24/170 AceView cDNA sequences (see all 170 ):
NM_006630 C21274 AA053288 AI151209 X78927 AY166787 BP365099 BQ012646 AH012544 BQ680058 BU608030 CF619307 CK903516 BC007303 AI186403 AY166788 M78106 AK023091 BU949912 CA942750 AI698737 AA234283 BC024197 BE299132
highest scoring ESTs for ZNF226 :AI978787 AA007348 AA007349 AA234283 AA385819 AA604064 AF228418 AF246126 AI276673 AI287547 Unigene Cluster for ZNF226:
Zinc finger protein 226 Hs.145956 [show with all ESTs ] Unigene Representative Sequence: BX648775 GeneLoc Exon Structure 5/12 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF226 (see all 12 ) ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b · 8c · 8d · 8e ^ 9a · 9b ^ 10a · 10b · 10c · 10d · 10e SP1 :           -   -     -   -   -               -   -   -   -             SP2 :           -       -   -   -               -   -   -   -             SP3 :           -   -       -   -                                 SP4 :           -   -     -   -   -               -   -                 SP5 :           -       -   -   -               -   -                
About this scheme ECgene alternative splicing isoforms for ZNF226 4 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000337433 (uc010ejg.2 uc002oyp.2 uc002oyn.2 uc002oyo.2 uc002oyq.2 uc002oyr.2 )ENST00000454662 (uc002oys.2 uc002oyt.2 ) ENST00000413984 ENST00000300823
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Expression for ZNF226 gene
(Experimental results according to
1 GeneNote
and GNF BioGPS ,
probe sets-to-genes annotations according to
2 GeneAnnot ,
3 GeneTide ,
Sets of similar genes according to GeneDecks ,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP ,
plus additional links to
SOURCE , and/or
GNF
BioGPS , and/or
EXPOLDB , and/or
UniProtKB ,
Primers from
OriGene and/or
SABiosciences
)
About This Section ZNF226 expression in normal and diseased human tissues 1 / 2 / 3
10 probe-sets matching ZNF226 gene
Affymetrix probe-set
Array
GeneAnnot data
GeneNote data
GeneTide data
# genes
Sensitivity
Specificity
Correlation
Length
Gb_Accession
Consensus
Uniqueness
Score
Rank
45519_s_at2 , 3
U95-B
1
1.00
1.00
0.88
0.69
AI287547
0.80
1.00
0.91
1
82852_at2 , 3
U95-E
2
1.00
0.81
0.93
1.32
AI978787
1.00
1.00
1.00
1
219603_s_at2 , 3
U133-A
1
1.00
1.00
--
--
NM_015919
0.60
1.00
0.82
1
233461_x_at2 , 3
U133-B
2
1.00
0.86
--
--
AK023091
0.80
1.00
0.91
1
231717_s_at2 , 3
U133-B
1
0.55
1.00
--
--
NM_016444
0.40
1.00
0.76
1
224004_at2 , 3
U133-B
1
0.46
1.00
--
--
AF246126
0.80
1.00
0.91
1
219603_s_at2
U133Plus2
1
1.00
1.00
--
--
--
--
--
--
--
233461_x_at2
U133Plus2
2
1.00
0.86
--
--
--
--
--
--
--
231717_s_at2
U133Plus2
1
0.55
1.00
--
--
--
--
--
--
--
224004_at2
U133Plus2
1
0.46
1.00
--
--
--
--
--
--
--
About this table
ZNF226 for expression About GeneDecksing Data from
Genenote  
(Publications) and GNF BioGPS About these images About these images CGAP SAGE TAG: GAATAAAAAA SOURCE GeneReport for Unigene cluster: Hs.145956 SABiosciences Custom PCR Arrays for ZNF226
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Orthologsfor ZNF226 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
and/or
5 MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase ,
Gene Trees according to Ensembl )
About This Section
Orthologs for ZNF226 gene from 2 species
Organism
Gene
Locus
Description
Human Similarity
NCBI accessions
cow (Bos taurus)
ZNF2261
--
zinc finger protein 226
77.58(n) 71.06(a)
789006 XM_001255251.1 XP_001255252.1
sea squirt (Ciona intestinalis)
AK114756.12
--
--
77.62(n)
AK114756.1
About this table Species with no ortholog for ZNF226 ENSEMBL Gene Tree for ZNF226 (if available)
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Paralogsfor ZNF226 gene (Paralogs according to 1 HomoloGene and 2 Ensembl , Pseudogenes according to 3 Pseudogene.org )About This Section Paralogs for ZNF226 gene ZNF222 2 ZNF284 2 ZNF229 2 ZFP112 2 ZNF223 2 ZNF155 2 ZNF45 2 ZNF664 2 ZNF235 2 ZNF227 2 ZNF221 2 ZNF239 2 ZNF224 2 ZNF234 2 ZNF285 2 ZNF214 2 ZNF233 2
ZNF226 for paralogs About GeneDecksing
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Genomic Variantsfor ZNF226 gene (SNPs according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE , and
UniProtKB ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Resequencing Primers from Qiagen )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Chr 19 pos Sequence Recs AA Chg Type More Recs Allele freq Pop Total sample More
About this table HapMap Linkage Disequilibrium images for ZNF226 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for ZNF226: --
QIAGEN SeqTarget long-range PCR primers for resequencing ZNF226
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Disorders & Mutationsfor ZNF226 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB ,
PharmGKB ,
Genatlas , GeneTests ,
Blood group antigen gene mutations by BGMUT ,
LSDB, HGMD, GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section --
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Medical Newsfor ZNF226 gene (Possibly Related Articles in
Doctor's Guide )
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Publicationsfor ZNF226 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 UniProtKB/TrEMBL , and/or
7 Novoseek )
About This Section 7 PubMed articles for ZNF226 gene integrated from 7 sources : (articles sorted by number of sources associating them with ZNF226) The DNA sequence and biology of human chromosome 19. (PubMed id 15057824) 1 , 2 Grimwood J.... Lucas S.M. (2004) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 Gerhard D.S....Malek J. (2004) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 Ota T.... Sugano S. (2004) Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters. (PubMed id 12743021) 1 , 2 Shannon M.... Stubbs L. (2003) An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142) 1 Ravasi T....Hayashizaki Y. (2010 Mar 5) Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560) 1 Kimura K.... Sugano S. (2006) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 1 Strausberg R.L....Marra M.A. (2002)
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External Searches for ZNF226 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing ZNF226 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing ZNF226 gene
(According to HUGE )
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Specialized Databases showing ZNF226 gene (According to ATLAS , HORDE , IMGT , MTDB, LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
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About This Section Patent Information for ZNF226 gene: Search GeneIP for patents involving ZNF226 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor ZNF226 gene (Antibodies, recombinant proteins, and assays by Millipore , Sigma-Aldrich , R&D Systems , Qiagen , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Epitomics , ProSpec , Uscn , Clones available from Millipore , Sigma-Aldrich , OriGene , GenScript , Sino Biological , PCR Arrays from SABiosciences , Drugs and/or compounds by Sigma-Aldrich , Tocris Bioscience , and/or
Enzo Life Sciences )About This Section
Search Tocris compounds for ZNF226
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