Aliases &
Descriptions
for ZNF430 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| zinc finger protein 4301 2 | | FLJ136591 2 | | MGC1332322 | | DKFZp762K0122 |
Export aliases for ZNF430 gene to outside databasesPrevious GC identifers: GC19P020979 GC19P020995 GC19P021203 |
Summaries
for ZNF430 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN430_HUMAN, Q9H8G1Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF430 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF430 gene promoter:
CP1A NF-Y NF-YA USF1 Pax-5 RFX1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF430
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19p12 Ensembl cytogenetic band: 19p12 HGNC cytogenetic band: 19p12ZNF430 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P020694: view genomic region
(about GC identifiers)
Start:
|
20,694,593 bp from pter |
End:
|
20,733,779 bp from pter |
Size:
|
39,187 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr19+ 21,203,497-21,241,653 |
RefSeq DNA sequence:- NC_000019.9 NT_011295.11
|
Proteins
for ZNF430 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: ZN430_HUMAN, Q9H8G1 (See
protein sequence)Recommended Name: Zinc finger protein 430 Size: 570 amino acids; 66319 Da
Subcellular location: Nucleus (Potential)
Sequence caution: Sequence=BAB14656.1; Type=Frameshift; Positions=293;
Secondary accessions: Q86V70Explore the universe of human proteins at neXtProt for ZNF430: NX_Q9H8G1
Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins (2 alternative transcripts):
NP_001166142.1 NP_079465.3
ENSEMBL proteins: ENSP00000261560
Human Recombinant Proteins
2 Gene Ontology (GO) cellular component terms (GO ID links to tree view): About this table
ZNF430 for ontologies About GeneDecksing
Antibodies for ZNF430:
Assays for ZNF430: |
Protein
Domains/
Families
for ZNF430 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF430 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9H8G1ProtoNet protein and cluster: Q9H8G1 1 Blocks protein family: IPB001909 KRAB box
UniProtKB/Swiss-Prot: ZN430_HUMAN, Q9H8G1Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 12 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Gene Function
for ZNF430 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
UniProtKB/Swiss-Prot: ZN430_HUMAN, Q9H8G1Function: May be involved in transcriptional regulation
4 Gene Ontology (GO) molecular function terms (GO ID links to tree view): About this table
ZNF430 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF430 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
SABiosciences Custom Pathway-Focused PCR Arrays for ZNF430
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF430
1 Gene Ontology (GO) biological process term (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
About this table
ZNF430 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF430 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for ZNF430
|
Transcripts
for ZNF430 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for ZNF430 gene (2 alternative transcripts): NM_001172671.1 NM_025189.3 Additional cDNA sequence: AK023721.1 AK127154.1 AK290475.1 AL832422.1 AY269787.1 BC111776.1 8 DOTS entries: DT.40290520 DT.433644 DT.121496377 DT.408247 DT.91643661 DT.101981534 DT.91857359 DT.95114454 24/26 AceView cDNA sequences (see all 26): BX504753 AI081603 BQ706964 AA314140 AU143734 AY269787 AU139909 BU193870 AL832422 AA375490 CD644291 NM_025189 BQ638610 AK023721 BQ636523 AA309966 BX471470 AW206930 AV707929 AI623759 AW963798 AW005593 CB963957 AU158222
 highest scoring ESTs for ZNF430:AA309966 AK023721 AL832422 AU139909 AU143734 AV707929 AW963798 AY269787 BM904065 BQ636523 Unigene Cluster for ZNF430: Zinc finger protein 430 Hs.466289 [show with all ESTs]Unigene Representative Sequence: NM_025189
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF430
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | - | | - | | - | | | | | |
About this scheme
ECgene alternative splicing isoforms for ZNF430
1 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000261560(uc002npj.2 uc002npk.2)
|
Expression
for ZNF430 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| ZNF430 expression in normal and diseased human tissues
1 / 2 / 3 5 probe-sets matching ZNF430 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 73716_r_at2, 3
|
U95-E |
1 |
0.62 |
1.00 |
1.00 |
1.00 |
AI623759 |
0.60 |
1.00 |
0.82 |
1 |
| 206829_x_at2, 3
|
U133-A |
2 |
1.00 |
0.95 |
-- |
-- |
NM_025189 |
0.60 |
1.00 |
0.82 |
1 |
| 238614_x_at2, 3
|
U133-B |
1 |
0.36 |
1.00 |
-- |
-- |
AW954842 |
0.40 |
1.00 |
0.76 |
1 |
| 206829_x_at2
|
U133Plus2 |
2 |
1.00 |
0.95 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
| 238614_x_at2
|
U133Plus2 |
1 |
0.36 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
ZNF430 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: AAAAAGCCAT
SOURCE GeneReport for Unigene cluster: Hs.466289
SABiosciences Custom PCR Arrays for ZNF430
|
Orthologs
for ZNF430 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for ZNF430 gene from 1 species
| Organism |
Gene |
Locus |
Description |
Human
Similarity |
NCBI accessions |
chimpanzee
(Pan troglodytes) |
ZNF4301 |
-- |
zinc finger protein 430 |
99(n)
98.24(a) |
737637 XM_001144468.1 XP_001144468.1 |
About this table Species with no ortholog for ZNF430
ENSEMBL Gene Tree for ZNF430 (if available) |
Paralogs
for ZNF430 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for ZNF430 gene
- ZNF852 ZNF4932 ZNF7332 ZNF1952 ZNF1002 ZNF922 ZNF6752 ZNF7322
- ZNF1382 ZNF5062 ZNF2732 ZNF6952 ZNF6262 ZNF432 ZNF6802 ZNF4922
- ZNF6822 ZNF6762 ZNF6812 ZNF1412 ZNF7362 ZNF2572 ZNF2542 ZNF7372
- ZNF724P2 ZNF982 ZNF7352 ENSG000001602292 ZNF7162 ZNF7142 ZNF5192 ZNF4292
- ZNF7302 ZNF6782 ZNF1172 ZNF7082 ZNF4312 ZNF902 ZNF7262
ZNF430 for paralogs About GeneDecksing
|
Genomic Variants
for ZNF430 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 19 pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for ZNF430 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for ZNF430
1 Indel: 26216 | | QIAGEN SeqTarget long-range PCR primers for resequencing ZNF430 |
|
Disorders & Mutations
for ZNF430 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Medical News
for ZNF430 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for ZNF430 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
5 PubMed articles for ZNF430 gene integrated from 7 sources:
(articles sorted by number of sources associating them with ZNF430)- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
|
External Searches for ZNF430 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF430 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF430 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF430 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for ZNF430 gene:
Search GeneIP for patents involving ZNF430
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF430 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
|
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