| rppaCellData {SuperCurve} | R Documentation |
This data set contains the expression levels of three proteins: AKT, ERK2, and beta catenin (CTNNB1) in 40 cell lines, measured in duplicate dilution series using reverse-phase protein arrays.
The data set also contains a description of the design of the reverse-phase protein array used in a set of experiments to measure protein levels in 40 different cell lines. Cell lysates were spotted on the array in duplicate in eight-step dilution series. The layout of the array consisted of a 4x10 grid of 4x4 subgrids. Each subgrid contained the duplicate dilution series for a single sample. Each of the identical top two rows of a subgrid contained the four most concentrated dilution steps (in decreasing concentrations from left to right), and the identical bottom two rows contained the four least concentrated dilution steps.
data(rppaCell)
The objects akt, c.erk2, and ctnnb1 are
objects of the RPPA class. The object design40
is an object of the RPPADesign class.
Bryan Hennessey and Gordon Mills
KRC