Testing Response to Chemotherapy in Breast Cancer, Pusztai et al 2004

This dataset consists of 620 sample and QC SELDI spectra used in Pusztai et al, "Pharmacoproteomic Analysis of Prechemotherapy and Postchemotherapy Plasma Samples from Patients Receiving Neoadjuvant or Adjuvant Chemotherapy for Breast Carcinoma", Cancer 2004;100:1814-22.
Summary of Study: Proteomic changes in NAF plasma were taken before and after paclitaxel or FAC (5-fluorouracil, doxorubicin, and cyclophosphamide) chemotherapy in patients with Stage I - III breast carcinoma to measure response to the chemotherapy. Samples of healthy women were taken also, to help identify breast carcinoma-associated protein markers. Full Abstract

All of the SELDI spectra have been exported as XML files using version 3.1.1 of the Ciphergen software. Further details are supplied in the README file.

Files available for download

README (13K text)
Clinical Information (13K zip file)
March03 Low Mass Scans (52.8M zip file)
March03 High Mass Scans (56.3M zip file)
June03 Low Mass Scans (47.2M zip file)
June03 High Mass Scans (52.8M zip file)


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