|Description||A comprehensive database of experimental-evidence-based Functional Impact of Somatic Mutations In Cancer|
|Last updated||January 5, 2018|
|Citation||Ng, P. K.-S., Li, J., Jeong, K. J., et al., Systematic Functional Annotation of Somatic Mutations in Cancer, Cancer Cell 33 (3) 450 (2018). https://doi.org/10.1016/j.ccell.2018.01.021|
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Human cancer is usually initiated by acquiring critical somatic mutations in tumor cells. In particular, Driver somatic mutations in the coding regions can modify protein functions, thereby resulting in a phenotypic effect on cell survival and proliferation. eFISMIC is a comprehensive database containing experimental evidence on the functional impacts of somatic mutations detected in human cancer.
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