LFSPRO-package |
TP53 mutation carrier estimation and cancer risk predictions |
calLK |
Calculate the likelihood Pr(D|G). |
calLK.cs |
Calculate the likelihood Pr(D|G) for cancer specific. |
calLK.mpc |
Calculate the likelihood Pr(D|G) of multiple primary cancers. |
cancer.data |
Built-in Cancer Information Data example |
cancer.type.all |
Predefined cancer types in LFSPRO. |
combined.risk.mpc |
Calculate the future cancer risk using the MPC model |
combinedata |
Combine the family information data and cancer information data |
convert.data |
Convert the combined family information data and cancer information data into separate data objects. |
fam.cancer.data |
Data object with Family and Cancer Information Example |
fam.data |
Built-in Family Information Data Example |
firstDegreeRelative |
First degree relatives |
invasive.cut |
Cutoff for malignant cancer |
lfs.cut |
Cutoff for Li-Fraumeni Syndrome spectrum cancer |
lfsChompret2009 |
The Chompret criteria for Li-Fraumeni syndrome |
lfsChompret2015 |
The Chompret criteria for Li-Fraumeni syndrome |
lfsClassic |
The Classic criteria for Li-Fraumeni syndrome |
lfspenet.2010 |
Penetrance for TP53 mutations |
lfspenet.cs.death |
Penetrance table for cancer-specific mutation with four competing risks (breast cancer, sarcoma, other cancers and death). |
lfspenet.cs.nodeath |
Penetrance table for cancer-specific mutation with three competing risks (breast cancer, sarcoma and other cancers). Default penetrance table in predicting cancer-specific risks. |
lfspro.cancer.type |
Predefined cancer types and the corresponding number in lfspro |
lfspro.mode |
Estimate TP53 mutation probability and predict cancer risk for families with Li-Fraumeni Syndrome with mode choice |
lfsproC |
Calculate the posterior probability of p53 mutations on the basis of family history |
lfsproC.cs |
Calculate the posterior probability of p53 mutations for cancer-specific risk prediction model on the basis of family history |
lfsproC.mpc |
Calculate the posterior probability of p53 mutations for multiple primary cancer on the basis of family history |
lkNoneAffect |
Likelihood for un-affected individuals |
lkNoneAffect.cs |
Likelihood for un-affected individuals for cancer-specific model |
parameter.mpc |
Estimated parameter for semiparametric recurrent event model of multiple primary cancers |
peelingRC |
Peeling interface in R. |
reformatForClassicChompret |
Reformat input data of LFSPRO for evaluation using the Classic or the Chompret criteria |
risk.cs |
Predict the cancer-specific risk |
risk.mpc |
Predict the risks of developing multiple primary cancers |
secondDegreeRelative |
Second degree relative |