TCMA
| Overview | |
| Description | A comprehensive resource for accessing, visualizing, and analyzing cancer mitochondrial genomic data. |
| Development Information | |
| URL | http://ibl.mdanderson.org/tcma/ |
| Language | JavaScript (with some R data processing) |
| Current version | 2.1 |
| License | Not required |
| Status | Active |
| Last updated | 2016-11-18 |
| News | it is online! |
| References | |
| Citation | Yuan et al. PCAWG. (2017). (submitted). |
| Help and Support | |
| Contact | Han Liang |
The Cancer Mitochondrial Atlas
Please click this link to enter the official TCMA site.
Mitochondria are essential cellular organelles that play critical roles in cancer development. Through International Cancer Genome Consortium, we performed a multidimensional characterization of mitochondrial genomes using the whole-genome sequencing data of ~2,700 patients across 37 cancer types and related RNA-sequencing data. Our analysis presents the most definitive mutational landscape of mitochondrial genomes. To facilitate mitochondria-related biological discoveries and clinical applications, we developed an open-access, user-friendly data portal “The Cancer Mitochondrial Atlas” (TCMA) for fluent exploration of the various types of molecular data characterized in this study.