TCMA
| Overview | |
| Description | A comprehensive resource for accessing, visualizing, and analyzing cancer mitochondrial genomic data. |
| Development Information | |
| URL | http://ibl.mdanderson.org/tcma/ |
| Language | JavaScript (with some R data processing) |
| Current version | 2.1 |
| License | Not required |
| Status | Active |
| Last updated | 2016-11-18 |
| News | it is online! |
| References | |
| Citation | Yuan et al. PCAWG. (2017). (submitted). |
| Help and Support | |
| Contact | Han Liang |
The Cancer Mitochondrial Atlas
Please click this link to enter the official TCMA site .
Mitochondria are essential cellular organelles that play critical roles in cancer development. Through International Cancer Genome Consortium, we performed a multidimensional characterization of mitochondrial genomes using the whole-genome sequencing data of ~2,700 patients across 37 cancer types and related RNA-sequencing data. Our analysis presents the most definitive mutational landscape of mitochondrial genomes. To facilitate mitochondria-related biological discoveries and clinical applications, we developed an open-access, user-friendly data portal “The Cancer Mitochondrial Atlas” (TCMA) for fluent exploration of the various types of molecular data characterized in this study.