We are currently interested in the following problems:
Computational approaches for next generation sequencing data analysis
Detection of structural and copy number variation in normal and cancer genomes
Accurate assembly of novel DNA or RNA sequence variants
Discovery and genotyping of sequence variants in heterogenous sample or population
Graphic approaches for RNA-seq analysis
Integrative characterization of genome and transcriptome
Computational approaches for single-cell omics
High quality bioinformatics and artificial intelligence tools for clinical sequencing and clinical decision support
Systems-biological cancer-genetic driver identification for biomarker and therapeutic target discovery