Department of Bioinformatics and Computational Biology

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We are currently interested in the following problems:

Computational approaches for next generation sequencing data analysis

Detection of structural and copy number variation in normal and cancer genomes

Accurate assembly of novel DNA or RNA sequence variants

Discovery and genotyping of sequence variants in heterogenous sample or population

Graphic approaches for RNA-seq analysis

Integrative characterization of genome and transcriptome

Computational approaches for single-cell omics

High quality bioinformatics and artificial intelligence tools for clinical sequencing and clinical decision support

Systems-biological cancer-genetic driver identification for biomarker and therapeutic target discovery