imogimap
| Overview | |
| Description | R package and RShiny application to calculate tumor-immune interaction scores based on mRNA expression profiles. |
| Development Information | |
| GitHub | korkutlab/imogimap |
| Language | R |
| Platforms | R |
| License | MIT |
| Status | Active |
| References | |
| Citation | Bozorgui, B., Kong, E.K., Luna, A., and Korkut, A. (2021) Mapping the Functional Interactions at the Tumor-Immune Checkpoint Interface. http://dx.doi.org/10.1101/2021.10.06.462889 |
| Help and Support | |
| Contact | Anil Korkut |
| Discussion | Issues On GitHub |
Immuno-oncology gene interaction maps, imogimap, is an R-based statistical analysis framework. Imogimap generates catalogues of maps that quantify the interactions at the tumor-immune interface. The goal of imogimap is to calculate tumor-immune interactions scores based on mRNA expression profiles of multi-sample data and rigorous statistical evaluation. The method quantifies combinatorial effects of tumor intrinsic onco-genic pathways and immune checkpoints on immune related phenotype in tumor micro-environment.
You can use imogimap’s Rshiny interactive web app directly following “our public domain”. To run locallym you can install our R library from GitHub with:
install_github('korkutlab/imogimap')This website is for educational and research purposes only.