Next-Generation Clustered Heat Map (NG-CHM)

NG-CHMs, developed by MD Anderson Cancer Center, provide significant advancements over traditional static heat maps. NG-CHMs offer a highly interactive and dynamic graphical environment for data exploration, making them superior for analyzing complex datasets.

Introductory Video

The following short video (less than three minutes) briefly summarizes the key features of the NG-CHM viewer.

Experiment with a sample NG-CHM (opens in new tab).

The Next-Generation Clustered Heat Map (NG-CHM) Viewer is a dynamic, interactive graphical environment for exploration of clustered or non-clustered heat map data in a web browser.

For a basic introduction to clustered heat maps, their components and uses, please see our Introduction to Clustered Heat Maps.

Documentation Navigation

If you wish to learn more about the NG-CHM Viewer, Builders, and related topics, click on a colored box in the diagram below or use the menu options in the left sidebar to open the indicated content.

Citing NG-CHMs

If you used NG-CHMs in Galaxy or GenePattern, please cite:

• Bradley M. Broom, Michael C. Ryan, Robert E. Brown, Futa Ikeda, Mark Stucky, David W. Kane, James Melott, Chris Wakefield, Tod D. Casasent, Rehan Akbani and John N. Weinstein, A Galaxy Implementation of Next-Generation Clustered Heatmaps for Interactive Exploration of Molecular Profiling Data. Cancer Research 77(21): e23-e26 (2017) (opens in new tab)

For all other uses, please cite:

• Michael C. Ryan, Mark Stucky, Chris Wakefield, James M. Melott, Rehan Akbani, John N. Weinstein, and Bradley M. Broom, Interactive Clustered Heat Map Builder: An easy web-based tool for creating sophisticated clustered heat maps. F1000Research 2019, 8 (ISCB Comm J):1750 (opens in new tab)

Credits

Research Scientists

• Bradley M. Broom
• Rehan Akbani
• John N. Weinstein
  
  

Software Developers

• MD Anderson
  • Chris Wakefield
  • James Melott
  • Mary Rohrdanz
  • Jun Ma

• In Silico
  • Michael Ryan
  • Mark Stucky

Administrative Support

• Glen Brosch
• Sylvain Laroche
  
  

Funding Support

• “Next-Generation” clustered Heat Maps for fluent, interactive exploration of omic data, U24CA199461, NIH/NCI ITCR (opens in new tab)
• TCGA: Grant number U24CA143883 from NCI/NIH
• The Michael & Susan Dell Foundation: The Lorraine Dell Program in Bioinformatics for Personalization of Cancer Medicine
• The H.A. Mary K. Chapman Foundation
• Anonymous donor for Computational Biology in Cancer Medicine